2024

November

  • What information is available to guide the practice of therapeutic drug monitoring for itraconazole, posaconazole, voriconazole, and isavuconazonium sulfate?
  • What are the latest updates and guideline recommendations in MASLD/MASH?
  • What are the current treatment recommendations for Mpox infections?

October

  • Update: Does the literature support the use of doxycycline for post-exposure prophylaxis against sexually transmitted infections?
  • Update: What is the role for commercially available fecal microbiota transplantation products in managing recurrent Clostridioides difficile infection?
  • Are there data to support dose intensification of golimumab for moderate to severe inflammatory bowel disease (e.g., 100 mg every 2 weeks)?

September

  • What evidence supports the efficacy and safety of donanemab for Alzheimer disease?
  • Is methylene blue a recommended non-catecholamine vasopressor to treat vasodilatory shock?
  • What is the comparative safety of IV bisphosphonates for the treatment of hypercalcemia in patients with renal dysfunction?

August

  • What is the recommended dosage of anakinra (Kineret) for secondary hemophagocytic lymphohistiocytosis (HLH)?
  • Are the sodium-glucose cotransporter-2 (SGLT2) inhibitors effective for reducing contrast-associated acute kidney injury?
  • What literature is available on oral beta-lactam therapy for gram-negative bacteremia?

July

  • What efficacy supports the use of liposomal bupivacaine for post-cesarean pain control?
  • What are the current recommendations for administration of live vaccines in patients receiving dupilumab?
  • What information is available on the newly approved Moderna RSV vaccine (mRESVIA®) and how does it compare with other currently available RSV vaccines?

June

  • What are the features of calculators used to estimated cardiovascular disease risk?
  • What is tianeptine, and are there recommendations for managing tianeptine misuse/withdrawal in the medical setting?
  • What are current recommendations on travel vaccine administration?

May

  • What literature is available on GLP-1 receptor agonists in the setting of bariatric surgery?
  • What are the differences in efficacy and safety of intranasal naloxone versus nalmefene?
  • What new evidence is available regarding intravenous iron replacement in patients with heart failure?

April

  • How do brexanolone and zuranolone compare in patients with postpartum depression?
  • Is intravenous hydroxocobalamin an effective treatment for vasoplegia-associated shock?
  • What information is available on vaccines for the prevention of RSV?

March

  • What are the Available and Emerging Phosphodiesterase 4 Inhibitors for COPD Treatment?
  • What are key pharmacologic recommendations in the management type 2 diabetes based on updated 2023 American Association of Clinical Endocrinologists (AACE) type 2 diabetes algorithm and 2024 American Diabetes Association (ADA) guidelines?
  • What information is available on gene therapies for treatment of beta-thalassemia?

February

  • Are there any guidelines supporting the use of metered dose inhalers (MDIs) versus nebulizers regarding infection transmission?
  • What information is available on novel gene therapies for treatment of sickle cell disease?
  • What is the role of colchicine in reducing the risk of cardiovascular events in adults?

January

  • What information is available on the off-label use of gabapentin and topiramate for alcohol use disorder?
  • What evidence supports the use of azithromycin for ruptured membranes in preterm prelabor?
  • Does the available evidence support the use of anakinra in the management of constrictive pericarditis?