2023

December

  • Is the use of piperacillin/tazobactam associated with risk of acute kidney injury?
  • What are institutional perioperative practices for patients with alpha-gal allergy?
  • What is the role of ketamine in the management of status epilepticus?

November

  • What are the latest updates and recommendations on vaccination against COVID-19?
  • Can thiazide diuretics cause increases in serum glucose?
  • What efficacy data are available on the use of tirzepatide for obesity?

October

  • Do data support the use of commercially available fecal microbiota transplantation products in managing recurrent Clostridioides difficile infection?
  • Is there a risk of intraoperative aspiration with the use of GLP-1 receptor agonists?
  • What data exists on the use of collagenase clostridium histolyticum (CCH) for the treatment of Peyronie’s disease?

September

  • Does Granulocyte Colony Stimulating Factor Increase the Risk of Bleomycin Induced Lung Injury?
  • A Summary of the 2023 American Geriatrics Society Updated Beers Criteria® for Potentially Inappropriate Medication Use in the Elderly
  • What are current best practices on holding metformin prior to and post contrast administration?

August

  • What literature supports the use of low-dose rifaximin in patients with hepatic encephalopathy?
  • What data exists on the use of buprenorphine and buprenorphine-naloxone for the treatment of kratom withdrawal?
  • Is there a preference between topical natamycin and topical voriconazole for first-line treatment of fungal keratitis?

July

  • What evidence supports the use of ketamine in pain management of vaso-occlusive episodes in patients with sickle cell disease?
  • What is the evidence for using greater than the FDA recommended dose of clobazam?
  • Does the literature support the use of doxycycline for post-exposure prophylaxis against sexually transmitted infections?

June

  • What evidence supports the use of neurokinin‐1 receptor antagonists for gastroparesis-related nausea and vomiting?
  • What is the optimal duration of antibiotics for complicated UTI in a male patient?
  • What is the update on long-term safety evidence with proton pump inhibitor use?

May

  • Is weight loss sustained after discontinuation of glucagon-like peptide 1 receptor agonists for obesity?
  • What information is available regarding the safety of Janus kinase (JAK) inhibitors in patients with rheumatoid arthritis?
  • What evidence is available supporting the use of vitamin D in the treatment of asthma?

April

  • What clinical evidence supports the use of lecanemab for Alzheimer disease?
  • What considerations should pharmacists make in relation to teplizumab use in patients with type 1 diabetes mellitus?
  • What data are available for sublingual dexmedetomidine in the treatment of acute agitation related to schizophrenia or bipolar disorder?

March

  • Should allopurinol be given simultaneously with rasburicase for tumor lysis syndrome?
  • Update: Can the intravenous formulation of vitamin K be administered orally?
  • What literature is available on the use of enteral immunoglobulin for the treatment of norovirus enteritis?

February

  • What data supports the use of alteplase 1 mg versus 2 mg for catheter occlusions?
  • Does the available data support the use of liposomal bupivacaine for analgesia during vasectomy and vasectomy reversal procedures?
  • Update: What evidence supports rectal indomethacin for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis?

January

  • What recent updates are available to guide decisions on use of immunosuppressant antirheumatic drugs perioperatively for orthopedic procedures?
  • What data are available for systemic tenecteplase in submassive pulmonary embolism?
  • What are current guideline recommendations for use of terlipressin in hepatorenal syndrome?