2018

December

  • Does administration of sodium bicarbonate to patients with severe metabolic acidosis yield a mortality benefit?
  • What data support use of topical tranexamic acid for epistaxis in adults?
  • What is the evidence for online vancomycin dose calculators?

November

  • What are important considerations for using cannabidiol for the treatment of pediatric seizures?
  • What are the 2018 SCCM guideline recommendations for pain, agitation/sedation, delirium, immobility, and sleep disruption (PADIS)?
  • Is intravenous lidocaine effective for renal colic in patients with urolithiasis?

October

  • What data are available to support administration of high-dose (>200 mg) iron sucrose in patients with non-dialysis-dependent chronic kidney disease?
  • What is the appropriate management of acute pain in a patient with opioid use disorder?
  • Probiotics and Clostridium difficile infections: What do we know now?

September

  • What is the emerging pathogen Candida auris and what should pharmacists know about it?
  • What role does intravenous magnesium play in the management of migraines?
  • What clinical data are available comparing meropenem 500 mg every 6 hours to meropenem 1000 mg every 8 hours?

August

  • What data support the use of andexanet alfa (ANDEXXA) for the reversal of factor Xa inhibitors?
  • What new data are available linking an increased infection risk with chronic opioid therapy?
  • Can intraoperative methadone reduce postoperative opioid requirements?

July

  • What is the efficacy and safety of IV acetaminophen when compared to oral acetaminophen?
  • What is the clinical efficacy of fish-oil containing lipid emulsion products compared to soybean oil-based lipid emulsion products for parenteral nutrition?
  • What is the evidence on the use of valbenazine (Ingrezza) for tardive dyskinesia?

June

  • What is the current evidence on using aromatherapy for treating postoperative nausea and/or vomiting?
  • What data are available to support etelcalcetide in hemodialysis patients with secondary hyperparathyroidism?
  • What guideline recommendations are available regarding perioperative multimodal analgesia (MMA)?

May

  • Update: What are aminophylline alternatives for the reversal of adenosine agonists used in pharmacologic stress testing?
  • In critically ill patients, do balanced solutions improve renal outcomes and decrease mortality when compared to normal saline?
  • What evidence is available for enoxaparin dosing for VTE prophylaxis in patients undergoing bariatric surgery?

April

  • Is there a potential for misuse and abuse with gabapentin (Neurontin®) and pregabalin (Lyrica®)?
  • What is the evidence behind the recent approval of the Shingrix vaccine?
  • What is the appropriate management of tetanus exposure?

March

  • Is one type of influenza vaccine more effective than another?
  • What is the role of Giapreza (angiotensin II) in shock?
  • What data are available for intravenous immune globulin (IVIG) in Clostridium difficile infection?

February

  • Are there data to support an increased risk of heart failure exacerbation/decompensation with pregabalin use?
  • What does the PRESERVE trial tell us about the prevention of contrast-induced acute kidney injury?
  • What data supports the efficacy and safety of meropenem-vaborbactam?

January

  • What is alpha-gal allergy and how does it impact medication therapy?
  • What is the evidence for the use of high-dose intravenous vitamin C for the treatment of cancer?
  • What are considerations for determining whether a drug may be administered via a midline catheter?