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  • What information has been yielded from the cardiovascular safety studies on new anti-hyperglycemic agents?
  • Should tranexamic acid be added to the standard of care in treating postpartum hemorrhage?
  • What evidence is available on adult dosing of vancomycin in obesity?


  • What is the evidence for decolonization with an alcohol-based nasal antiseptic?
  • What evidence supports combining insulin and other antidiabetic medications in adults with type 1 diabetes?
  • What is the appropriate management of rabies exposure?


  • What is the appropriate management of hemorrhagic cystitis?
  • How can sodium acetate be used as a substitute for sodium bicarbonate, and what other strategies are recommended for sodium bicarbonate shortage management?
  • What are cardioplegia solutions?


  • How is acute kidney injury defined in pediatric patients?
  • What data are available on use of N-acetylcysteine in the management of non-acetaminophen drug-induced liver injury?
  • What are the new data regarding risk of sudden death in heart failure?


  • What is the role of minocycline in the treatment of multidrug resistant organisms?
  • ​What evidence supports the use of coenzyme Q10 supplementation to prevent or treat statin-associated myopathy?
  • What evidence is available on the use of intravenous sildenafil for pulmonary arterial hypertension?


  • Is pregabalin effective for the treatment of sciatica pain?
  • What evidence is available to support the use of anti-factor Xa levels instead of activated partial thromboplastin time for monitoring of intravenous unfractionated heparin therapy in adults?
  • Are there any new safety concerns with antibiotics in pregnancy?


  • Can olanzapine be administered intravenously for the management of acute agitation?
  • What evidence supports the use of intravenous sub-dissociative-dose ketamine for pain in the emergency department?
  • What is the available evidence for the use of alteplase for occlusion of peritoneal dialysis catheters?


  • What is the role of bezlotoxumab in treating Clostridium difficile infections?
  • What is the evidence for use of high-dose vitamin C in critically ill patients?
  • How does brivaracetam compare to other antiepileptic agents in treating refractory partial onset seizures (POS)?


  • What evidence is available for the use of aprepitant (Emend) compared to other antiemetics for the prevention of postoperative nausea and vomiting?
  • What handling precautions should be taken when preparing monoclonal antibody drugs?
  • What are the American Heart Association’s recommendations for managing NOACs in acute care and peri-procedurally?


  • What evidence evaluates the use of procalcitonin to guide antibiotic duration in patients with hospital-acquired or ventilator-associated pneumonia?
  • What is the usual clinical presentation, diagnosis, and management of norovirus infection?
  • Which is the best method for administration of pancreatic enzyme replacement products by enteral feeding tube?


  • Can direct oral ant​icoagulants be prescribed to patients taking carbamazepine?
  • Are there data to support the treatment of Pseudomonas infections with cefepime 1 gram every 6 hours vs. 2 grams every 8 hours?
  • What are the treatment options for post-operative shivering?


  • What are the updated recommendations for the role of PCSK9 inhibitors in the management of hypercholesterolemia?
  • What literature supports the use of liposomal bupivacaine in transversus abdominis plane nerve blocks?
  • What evidence is available for using direct oral anticoagulants in HIT?