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2025

December

  • What information is available on IV fosfomycin for the treatment of complicated urinary tract infections?
  • Is there evidence to support the use of piperacillin-tazobactam for the treatment of necrotizing pancreatitis?
  • Overview of the 2025 Hypertension Guidelines

November

  • What is the role of azelastine nasal spray in the management of COVID-19?
  • What is the latest information on subcutaneous semaglutide for MASLD/MASH?
  • What do national and international health organizations say about the link between Tylenol (acetaminophen) use and autism?

October

  • What is the available literature on the risk of inhaled corticosteroid (ICS)-induced adrenal insufficiency in preterm infants with bronchopulmonary dysplasia (BPD)?
  • What data is available regarding partner treatment to prevent recurrence of bacterial vaginosis?
  • What new drugs are available for the management of hereditary angioedema?

September

  • What evidence and recommendations support the use of clesrovimab for prevention of RSV?
  • What information is available about the use of suzetrigine, an oral sodium channel blocker, for moderate to severe acute pain in adults?
  • What is the role of daptomycin for vancomycin-resistant Enterococcus (VRE) prophylaxis in liver transplant recipients?

August

  • What conservation strategies are available if medication administration filters are on limited supply?
  • Update: Can a simplified 2-bag acetylcysteine approach improve tolerability in acetaminophen overdoses?
  • What Are the Safety Concerns Regarding Compounded GLP-1 Receptor Agonists?

July

  • What are the most up to date guideline recommendations for the treatment of Lyme disease?
  • What evidence evaluates rectal administration of P2Y12 inhibitors?
  • Update: What is the Role of Tranexamic Acid in Patients with Acute Gastrointestinal Bleeding?

June

  • What are the expanded recommendations for pneumococcal conjugate vaccine use in adults?
  • What information is available on the new drug gepotidacin for treatment of uncomplicated urinary tract infections?
  • Update: What data support the use of andexanet alfa (ANDEXXA) for the reversal of factor Xa inhibitors?

May

  • What data are available on apixaban for treatment of left ventricular thrombus?
  • Do long-acting injectable antipsychotics have a higher risk of QTc prolongation than immediate-acting antipsychotics?
  • What evidence supports the use of colchicine for the secondary prevention of cardiovascular events?

April

  • What literature supports a maximum dose of unfractionated heparin in patients with obesity?
  • How should metronidazole be used for chronic wound odor?
  • What information is available regarding yellow fever vaccine administration in patients with egg allergy?

March

  • What information is available on the use of omalizumab for IgE-mediated food allergy?
  • What evidence evaluates the use of Paxlovid™ (nirmatrelvir/ritonavir) in severe renal impairment?
  • What guidelines are available about ketamine use in the management of complex regional pain syndrome?

February

  • What are the recommendations to identify and manage Shoulder Injury Related to Vaccine Administration (SIRVA)?
  • Is there evidence to support initiation of remdesivir after 7 days in hospitalized patients with severe COVID-19?
  • Is there literature, specifically guidelines, available on how to medically manage adverse reactions associated with intravenous iron?

January

  • Is there evidence supporting the use of remdesivir for longer than 10 days in the treatment of COVID-19?
  • What are the latest guideline recommendations for the treatment of Helicobacter pylori infection in the U.S.?
  • What information is available regarding the new antipsychotic xanomeline/trospium?