2010

December

  • Should antibiotics be used in all patients with COPD exacerbations?
  • What does the ACC/ACG/AHA 2010 Expert Consensus Document recommend regarding the concomitant use of PPIs and thienopyridines?
  • What changes have been made to the AHA guidelines for cardiopulmonary resuscitation?
  • What are the treatment options for post-operative shivering?

November

  • Is there information on deviating from the standard protocol for N-acetylcysteine treatment of acetaminophen overdose?
  • What do the New Practice Guidelines for Chronic Pain Management Recommend?
  • What are the new warnings for bisphosphonates?
  • What are the CURRENT-OASIS 7 study findings regarding dose comparisons of clopidogrel and aspirin in acute coronary syndromes?

October

  • Are antivirals safe to use during the first trimester of pregnancy?
  • What are the differences among modes of renal replacement therapy?
  • What are current recommendations to minimize risk of nephrogenic systemic fibrosis with gadolinium-based contrast agents?
  • What are the new recommendations for the 2010-2011 Flu Season?

September

  • Use of bladder irrigations for treatment of superficial bladder infections
  • How do you safely and effectively use elastomeric pain pumps?
  • Updated perinatal guidelines for HIV-1 infected women
  • Should quinine be used for treatment of nocturnal leg cramps?

August

  • What antiviral therapy can be given to a patient with allergy to acyclovir?
  • Do angiotensin receptor blockers (ARBs) increase cancer risk?
  • How is intrapleural doxycycline used to treat pleural effusions?
  • What is the available evidence for the use of rifaximin (Xifaxan) for the treatment of hepatic encephalopathy?

July

  • What is the available evidence for the use of sodium thiosulfate for calciphylaxis?
  • What products can be used to unclog feeding tubes?
  • Do proton pump inhibitors increase the risk of Clostridium difficile infections?
  • STAT-C compounds—focus on telaprevir

June

  • How do the benefits and risks of alteplase therapy for ischemic stroke change over time?
  • Agents for the treatment of disorders of blood coagulation
  • How should a patient with G6PD deficiency be managed perioperatively?
  • Are there data to support fluconazole desensitization?

May

  • What is the optimal timing of antibiotics for the prevention of postoperative infections for cesarean delivery?
  • Clostridium difficile clinical practice guidelines: summary of treatment recommendations
  • What weight should be used when dosing unfractionated heparin for treatment of thromboembolism in obese patients?
  • Intensive blood pressure and lipid control in patients with type 2 diabetes mellitus: results of the ACCORD Lipid and ACCORD BP trials.

April

  • Are there any data to support using intravenous (IV) azithromycin in children <16 years of age?
  • What is the latest literature comparing dopamine and norepinephrine in the treatment of shock?
  • Practice guidelines for the treatment of complicated intra-abdominal infections: summary of drug therapy
  • What are the most recent data regarding the safety and efficacy of long-acting beta2-agonists in the management of asthma?

March

  • What is the cross-reactivity of cephalosporins and carbapenems in a patient with a penicillin allergy?
  • What are the latest recommendations for the prevention of torsade de pointes in the hospital setting?
  • What are the REMS requirements for hospitals dispensing ESAs to patients with cancer?
  • Dihydroergotamine in the treatment of migraines: recommended dosing strategies

Feburary

  • What revisions have been made to the ADA’s 2010 Clinical Practice Recommendations?
  • What is the current status of erythropoiesis-stimulating agents in chronic kidney disease?
  • Does Voluven (hydroxyethyl starch 130/0.4) cause less bleeding than hetastarch?
  • What are the clinical data for dronedarone (Multaq)?

January

  • What are the ARBITER 6-HALTS study findings regarding the clinical efficacy of ezetimibe?
  • The Food and Drug Administration’s Safe Use Initiative
  • Revised ACC/AHA/SCAI Guidelines Released
  • Wilate: a new therapy for von Willebrand disease